Reducing capsular thickness and enhancing angiogenesis around implant drug release systems.
نویسنده
چکیده
Biological encapsulation and the foreign body reaction can impair the performance of implanted drug release devices. In this article, the classic definition of biocompatibility is questioned. Examples are presented of biomaterials showing unique healing behavior. A new paradigm for biomaterials healing is proposed in which non-specific protein adsorption is inhibited and matricellular proteins are controlled at the surfaces of implants.
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عنوان ژورنال:
- Journal of controlled release : official journal of the Controlled Release Society
دوره 78 1-3 شماره
صفحات -
تاریخ انتشار 2002